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Nettle™ & PMDD: What the Research Says + Q&A

Nettle™ & PMDD: What the Research Says + Q&A

When: November 6, 2025 at 12 PM ET

Ticket Price: $15.00 + Eventbrite fees

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Event Description: This webinar will explore new research into non-invasive brain stimulation for Premenstrual Dysphoric Disorder (PMDD). We will review the recent study Validation of a Non-Invasive Brain Stimulation Device (Nettle™) to Manage Symptoms of PMDD and discuss what it means for future treatment options.

Following the review, participants attending live have the opportunity to take part in a Q&A with Emilé Radyte, PhD, CEO & Founder of Samphire Neuroscience, and inventor of the Nettle™ device.

After this session, you will:

  • Understand the neuroscience of PMDD, including the latest research on how cyclical hormone sensitivity impacts brain function and emotional regulation.

  • Understand the key barriers to accurate PMDD diagnosis, including the need for cycle tracking and symptom overlap with other conditions like ADHD and bipolar disorder.

  • Evaluate the potential role of the Nettle™ device as a non-invasive, non-hormonal, and non-medication treatment option for PMDD, especially for those who don't respond well to current therapies. This will include an exploration of results from a recent clinical trial assessing Nettle specifically for PMDD, where it is currently approved for pain and mood symptoms.

  • Identify the challenges and opportunities in integrating new PMDD treatments like Nettle™ into healthcare systems, including the importance of clinician awareness, patient advocacy, and coordinated care pathways.

Intended Audience: Designed for anyone who wants to better understand PMDD with an interest in research, mental health, and emerging health technologies.

Hosted by: IAPMD and Emilė Radytė, PhD

Dr Emilė Radytė is a neuroscientist and science communicator whose work explores how hormonal changes shape brain function, mood, and behavior. A graduate of Harvard and Oxford, her research has focused on psychiatric applications and neurocognitive markers of response to brain stimulation treatments for depression.

She is the co-founder of Samphire Neuroscience, a company on a mission to provide brain-based solutions for women across the lifecycle. Its first product, Nettle™, is a CE-marked at-home neurotechnology device for the relief of menstrual-related pain and mood symptoms. Nettle™ is currently part of a PMDD study led by Queen Mary University of London, now in the reporting phase, and an NHS pilot study for endometriosis-related pain. Emilė is deeply passionate about advancing women’s health and closing the gender gap in neuroscience through evidence-based innovation.

Will this be recorded? Yes, this event will be recorded and a link will be shared with all who register.

Get 15% off Nettle™ with promo code IAPMD15 and give back while you shop! A percentage of every purchase made with this code helps fund IAPMD’s work to support and empower those affected by premenstrual disorders. Purchase the Nettle™ here.


Thanks to the generous support of the Christina Bohn Foundation, we’re able to offer a limited number of complimentary tickets to help make this event accessible to everyone who wishes to join. Please reach out to events@iapmd.org for more information.

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October 29

Premenstrual Disorders and Perimenopause

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November 30

PMDD and Social Life: Navigating Connection, Expectations, & the Festive Season